Parkinson’s disease remains a very difficult condition. The only partially successful treatment was orthomolecular. Based upon the hypothesis that it was caused by a deficiency of dopamine, l-dopamine was tried, but the first double blind controlled trials proved that it was not effective. However, patients had not been given nearly enough to do any good. This is like what happens when the establishment tries to test vitamins and uses small vitamin-like doses, when the early positive results were all obtained with much larger orthomolecular doses. Larger doses of l-dopa were successful. But in contrast to vitamins, the side effects of this neurohormone are very dangerous. L-dopamine is oxidized into dopachrome in the brain; this is toxic to cells and is an hallucinogen. Many patients given too much became psychotic. And because it is toxic to brain cells, it also hastens the onset of more degeneration and even death1. Therefore it is not surprising that, like adrenochrome, it can cause psychotic reactions. Niacin protects the body against the toxic effect of adrenochrome. For this reason I have used it in conjunction with the l-dopa to protect these patients. The presence of dopachrome increases the need for niacin, which must be replaced. The other nutrient that is now standard treatment is coenzyme Q10, using up to 1200 milligrams daily.
Thorne2 reported that a prominent divorce lawyer was disbarred after taking more than $600, 000 from her clients’ trust funds. She has been prescribed medication for her Parkinson’s disease, which made her paranoid and changed her behaviour. She became a compulsive shopper, thought that her husband was having an affair and had tried to kill herself. Her doctor reported to the disbarment hearing that she had been changed by her medication. The medication is not listed but I assume that it was l-dopa since this is the accepted universal treatment. Had she been under my care she would have been on niacin as well and this would have protected her against the psychosis induced by the l-dopa, which was oxidized in her body to dopachrome. This unfortunate lawyer was destroyed by her disease and by the side effect of the treatment that she was given.
Hoffer A and Foster HD. Feel Better, Live Longer With Niacin. In press, CCNM, Toronto, Ont. 2006, Chapter 10.
1 Foster HD & Hoffer A. The two faces of L-Dopa: benefits and adverse side effects on the treatment of Encephalitis lethargica, Parkinsons’ disease, multiple sclerosis and amytrophic lateral sclerosis. Medical Hypothesis 2004;62:177-181